Study of lipid profile, enzymatic antioxidant and oxidative stress in cardiovascular diseases

Author(s): Binod Mahato, Chaudhary B. L and Brij Nandan Singh

Abstract

Cardiovascular disease is one of the major causes of death in the India, therefore present study, was aimed to study the lipid profile, enzymatic antioxidant and oxidative stress in cardiovascular diseases. The study was carried out in the Department of Biochemistry and Medicine MGM Medical College and Hospital, Mumbai. 5ml. Blood sample was drawn into plain vacutainers and was utilised for estimation of lipid profile, oxidative stress markers concentration and antioxidant enzymes activities. The mean values of Total cholesterol, LDL TG, and MDA were significantly increased in CVD patients as compared to control (p<0.0001) and HDL, NO, SOD, CAT in CVD patients were significantly decreased as compared to control (p<0.0001). The present study reveals the importance of determining the lipid profile, free radicals and antioxidant status in CVD to enable the formulation of specific therapies for early intervention and better management of disease.

10.21746/ijbio.2016.08.007

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