MANGIFERIN QUANTIFICATION IN SOME SWERTIA SPECIES COLLECTED FROM SOUTH-WEST ZONE OF MAHARASHTRA

Author(s): Aruna Nangare and VD Mendhulkar

Abstract

The present work deals with the analytical aspect of three species of Swertia viz. Swertia densifolia Griseb, Swertia minor Knobl., and Swertia lawii Syn. collected from southwest-zone of Maharashtra for quantification of mangiferin content. A xanthone derivative, mangiferin exhibits diverse pharmacological activities like anti-diabetic, anti-HIV, anti-cancer and antioxidant properties. Quantification of xanthone compound mangiferin was done by High Performance Liquid Chromatography method using methanol: water solvent system as the mobile phase. Injection volume for species as well as standard Samples was 10μl and flow rate of 1ml/min at room temperature. Standard calibration curve was generated for quantification of Mangiferin in studied samples. Leaf extract samples were used for the analysis. The highest quantity of Mangiferin, 6.02mg/g was estimated in Swertia densifolia while Swertia minor indicated the estimate of 4.21mg/g whereas, Swertia lawii contains 0.24mg/g of mangiferin, indicating the lowest content among the three species.

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