Lipid profile in psoriasis: a case control study

Author(s): Kailash Bhatia*, Suneel Malpani, Ashish Singh, Zainab Hussian Safderi, Susmit Kosta, Ravindra Kumar

Abstract

Psoriasis is associated with an atherogenic lipid profile but longitudinal changes in lipids around disease onset are unknown. The purpose of our study is to examine the effect of psoriasis onset on serum lipid profiles. We compared changes in lipid profiles in a population based 94 patients with psoriasis vulgaris and 103 non-psoriasis subjects. The total cholesterol and low-density lipoprotein and high-density lipoprotein cholesterol levels were significantly higher in psoriatic patients (P < 0.05). Serum triglyceride levels were almost similar in both groups. This study, like other previous studies, shows that high serum lipid level is significantly more common in psoriasis. This fact may be responsible for higher prevalence of cardiovascular accident in psoriatic patients. It may be useful to do early screening and treatment of hyperlipidemia in psoriasis to prevent the atherosclerosis and its complications. These changes are unlikely to be caused by lipid profile treatment alone and require further exploration.

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