Hematological manifestations in non-hematological malignancies
Author(s): Anu Gupta, Tajinder Singh*, Sachin Gupta
Abstract
Malignancy is one of the principal causes of death both in developed and developing countries. An abnormal hematological picture may be the first manifestation of many non-hematological malignancies. The present study was conducted to detect the hematological abnormalities in patients with solid tumors and to correlate these parameters with the histological diagnosis and clinical stage of the tumor. Fifty cases of Non-hematological malignant tumors were taken up in the study. Their blood samples were taken at the time of diagnosis i.e before the treatment and detailed hematological investigations were done. Diagnosis of these patients were confirmed by histological and cytological examination. Out of these 50 patients, 27 were females and 23 were males. In our study, anemia was observed as an important hematological finding in almost every malignancy, out of total 50 cases with various non-hematological malignancies, 37 were anemic (74%). Leucocytosis was detected in 25 out of 50 cases (50%) and increased platelet count (Thrombocytosis) was found in 17 cases out of total 50 (34%) in the present study. The present study showed a definite association of hematological manifestations viz. anemia, leucocytosis and thrombocytosis with various non-hematological malignancies, which if detected early in the course of disease can prevent associated morbidity and mortality and surely help in better patient care.
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