Green synthesis of nanostructured materials for antibacterial and antifungal activities..

Author(s): Ayeshamariam A*, Tajun Meera Begam M., Jayachandran M., Praveen Kumar G., M. Bououdina

Abstract

New materials hold the key to fundamental advances in antibacterial and antifungal activities, both of which are vital in order to meet the challenge of global warning of microorganism’s advantages and limitations and the finite nature of medicinal plants. The use of additive to augment the effect of a synthetic or natural drug candidate is well known. Here we report the use of nanoparticles of tin oxide (SnO2) to enhance the antibacterial and anti fungal potency of Alovera extract when compared to bulk tinoxide (SnO2). The possible advantage and limitations of this result will be discussed. It is hoped that this study would lead to the establishment of nanomaterial compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin. Antibacterial activity of Alovera extracts was checked against these gram positive isolates of Staphylococcus aureus, Escherichia Coli E, Salmonella Typhi, Streptococcus pyogenes and gram negative isolates of Pseudomonas Aeruginosa. We observed that effective anti-bacterial and anti-fungal activities for SnO2 nanoparticles, particularly for Streptococcus pyogenes microorganisms and antifungal microorganisms of Aspergillus niger, Mucor indicus microorganism than bulk SnO2.

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