Cover Image

A 1-year clinicoepidemiological prospective analysis of Breast lesions by Fine Needle Aspiration Cytology at a tertiary care center

Akshay Agarwal*, Pathan Saira Bano, Prashant Jawade

Abstract


Fine Needle Aspiration Cytology (FNAC) or biopsy usually confirms the diagnosis of breast lesions with both modalities having its own merits and demerits. The objective of the current study was to evaluate the diagnostic utility of FNAC in all patients presenting with breast lesions. The aim of the study was to analyze the varied breast lump lesions that presented to us for FNAC in 1-year duration. All patients of both sexes presenting with a palpable breast lump or nipple discharge were included in the study. Duration of the study was from 1st January 2014 to 31st December 2014. The Data was analyzed using Excel and expressed as percentage (%), Mean and median. The mean age of presentation was 33 years. Out of the 141 FNAC performed, 29 cases had indefinite diagnosis. Excluding these, the most common lesion was fibroadenoma (49 out of 112) followed by malignancy (16 out of 112). FNAC still remains an important tool to evaluate breast lesions because of its cost effectiveness, speedy diagnosis and minimally invasive quality.

Keywords


Fine needle aspiration cytology; Breast; breast cancer; benign

Full Text:

PDF

References


Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, Rebelo et al GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11.

J. C. Litherland, “Should fine needly aspiration cytology in breast assessment be abandoned?’ Clinical Radiology 2002, 57;2: 81-84.

Wallis M, Tarvidon A, Helbich T, Schreer I: Guidelines from the European Society of Breast Imaging for diagnostic interventional breast procedures. Eur Radiol 2007, 17, 581-588.

Y.H. Yu, W. Wei, and J.L. Liu “Diagnostic value of fine-needle aspiration biopsy for breast mass: a systematic review and meta-analysis,” BMC cancer, 2012, 12; 41.

S. H. Parker, A. T. Stavros, and M. A. Dennis, “Needle biopsy techniques,” Radiologic Clinics of North America, 1995, 57; 2, 1171-1186.

Bean GR, Scott V, Yee L, Ratliff-Daniel B, Troch MM, Seo P et al Retinoic acid reciptor-beta2 promoter methylation in random periareolar fine needle aspiration. Cancer Epidemiol Biomarkers 2005, 14, 790–798.

Masood S, Frykberg ER, McLellan GL, Scalapino MC, Mitchum DG, Bullard JB: Prospective evaluation of radiologically detected fine needle aspiration biopsy of nonpalpable breast lesions. Cancer 1990, 66, 1480–1487.

Sun W, Li A, Abreo F, Turbat-Herrera E, Grafton WD: Comparison of fine-needle aspiration cytology and core biopsy for diagnosis of breast cancer. DiagnCytopathol 2000, 24, 421–425.

Kuenen-Boumeester V, Menke-Pluymers M, de Kanter AY, Obdeijn IM, Urich D, Van Der Kwast TH: Ultrasoundguided fine needle aspiration cytology of axillary lymph nodes in breast cancer patients. A preoperative staging procedure. Eur J Cancer 2003, 39, 170–174.

Ciatto S, Brancato B, Risso G, Ambrogetti D, Bulgaresi P, Maddau C, et al Accuracy of fine needle aspiration cytology (FNAC) of axillary lymph nodes as a triage test in breast cancer staging. Breast Cancer Res Treat 2007, 103, 85–91.

Van Rijk MC, Duerloo EE, Nieweg OE, Gilhuijs KG, Peterse JL, Rutgers EJ et al Ultrasonography and fine-needle aspiration cytology can spare breast cancer patients unnecessary sentinel lymph node biopsy. Ann Surg Oncol 2005, 13, 31–35.

Dixon JM, Anderson TJ, Lamb J, Nixon SJ, Forrest APM: Fine needle aspiration cytology, in relationship to clinical examination and mammography in the diagnosis of solid breast mass. Br J Surg 1984, 71, 593–596.

Farshid G, Rush G: The use of fine-needle aspiration cytology and core biopsy in the assessment of highly suspicious mammographic microalcifications. Cancer Cytopathol 2003, 99, 357–364.

Krishnamurthy S: Current applications of future prospects of fine-needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer. Cancer Cytopathol 2009, 12, 451–462.

Alvarez S, An˜orbe E, Alcorta P, Lo´pez F, Alonso I, Corte´s J: Role of sonography in the diagnosis of ancillary lymph node metastases in breast cancer: a systematic review. AJR Am J R oentgenol 2006, 186, 1342–1348.

Jain A, Haisfield-Wolfe ME, Lange J, Ahuja N, Khouri N, Tsangaris T et al The role of ultrasound-guided fine-needle aspiration of axillary lymph nodes in the staging of breast cancer. Ann Surg Oncol 2007, 15, 462–471.




DOI: http://dx.doi.org/10.21746/ijbio.2015.12.0013

Refbacks

  • There are currently no refbacks.




Copyright (c) 2015 International Journal of Bioassays

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

International Journal of Bioassays is a member of the Publishers International Linking Association, Inc. (PILA), CROSSREF and CROSSMARK (USA). Digital Object Identifier (DOI) will be assigned to all its published content.