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Evaluation of thyroid dysfunction in patients suffering from diabetes mellitus in a tertiary care hospital

Tajinder Singh*, Jaswant Kaur

Abstract


Diabetes mellitus is an endocrine disorder so it is prone to affect other endocrine functions, one of which is thyroid function. The present study was conducted to estimate thyroid hormone levels in diabetes mellitus (Both type 1, type 2) and to compare these levels with normal population (control). Fasting blood samples from 50 diabetic subjects (7 type 1 and 43 type 2) and 50 non diabetic control were analysed. Out of the 50 diabetic patients for the study, 21 are males (3 in type1 and 18 in type 2) and 29 are females (4 in type 1 and 25 in type 2). Of these 31(62%) are euthyroid, 7 (14.0%) had primary hypothyroidism (6females and 1male),1(2.0%) had primary hyperthyroidism(only 1male), 9(18%)  had  subclinical hypothyroidism (1male and 8 females), 2(4.0%) had subclinical hyperthyroidism(1male and 1female). Maximum cases were of hypothyroidism (subclinical and clinical) seen in the study group. There were only 2 subjects in control groups having thyroid disorders. So thyroid disorders in study group is highly significant as compared to control group. As the level of Glycosylated Hb (HbA1c) increases the chances of thyroid disorders also increases. There is high prevalence of thyroid disorders in diabetes. Thyroid disorders are more common in females and most common thyroid disorder is hypothyroidism. The association of thyroid disorders are more frequent in diabetics who have deranged metabolic control. 

Keywords


Thyroid hormones; Type 1 DM; Type 2 Diabetes Mellitus Glycosylated Hb.

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References


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DOI: http://dx.doi.org/10.21746/ijbio.2014.12.005

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