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Significance of seroprevalence of hepatitis b in HIV positive patients

Sureena Chouhan, Geeta Parihar, Seema Srivastava*

Abstract


Study was undertaken to find out the significance of the co-infection of HBV/ HIV. HBV/HIV co-infection is a growing public health concern because both the diseases spread in a similar way. This co-infection has an increased risk of fibrosis and cirrhosis. Out of 256 samples 12 samples were positive for HBV i.e. 4.68% positivity. Highest prevalence was found among age group 36-45  years (50%), while not a single HBV positive case were recorded in less than 15 years of age. 6 out of 12  patients were between of 36-45 year of age, which implies that HBV infection is more common in adults. These observations will help the health professionals to deal better with HBV & HIV co-infected patients and will reinforces the need of prevention programs, which also lead to reduction in prevalence of HBV in HIV infected patients.

Keywords


Seroprevalence; HIV-HBV co-infection; cirrhosis; fibrosis

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References


Alter MJ, Epidemiology of viral hepatitis and HIV co-infection. J. Hepatol. 2006: 44 (1 suppl): S6-9.

Benhamou Y, Hepatitis B in the HIV co-infected patients. JAIDS 2007; 45/ suppl 2): S57-S65 and S66-S67).

Blumberg BS, Alter HJ & Visnich S, A "new" antigen in leukemia sera. J. Amer. Med. Ass. 191:541-6, 1965. [Institute for Cancer Research, Philadelphia, PA and NIH, Bethesda, MD]

Bodsworth NJ, Cooper DA, Donovan B, The influence of human immunodeficiency virus type 1 infection on the development of the hepatitis B virus carrier state .J infect Dis 1991; 163: 1138-1140.

Bodsworth N, Donovan B, Nightingale BN, The effect of concurrent human immunodeficiency virus infection on chronic hepatitis B: a study of 150 homosexual men. J infect Dis 1989 oct; 160(4): 577-82.

Bran N, Fox R, Xiao P et al., Presentation and outcome of hepatocellular carcinoma in HIV infected patients: a US-Canadian Multicentre Study. J Hepatol 2007; 47: 527-537.

Bruix J; Sherman M. Management of Hepatocellular Carcinoma. Hepatology 2005; 42: 1208-1236.

Eskild A, Magnus P, Peterson G et al., Hepatitis B antibodies in HIV infected homosexual men are associated with more rapid progression to AIDS 1992 JUN : 6(6) : 571-4.

Gatanaga H, Yasuoka A, Kikuchi Y, Tachikawa N, Oka S. Influence of prior HIV-1 infection on the development of chronic hepatitis B infection. Eur J Clin Microbiol Infect Dis 2000; 19:237-9.

Gilson RJ, Hawkins AE, Beecham MR, et al., Interaction between HIV and Hepatitis B virus in homosexual men effects on the natural history of infection. AIDS. 1997 Apr; 11(5): 597-606.

Hadler SC, Judson FN, O Malley PM, et al., Outcome of Hepatitis B virus infection in homosexual men and in relation to prior human immunodeficiency virus infection. J infect Dis 1991 Mari 163(3): 454-9.

Konopnicki D, Mocroft, de WS et al., Hepatitis B and HIV: Prevalence, AIDS progression, response to highly active antiretroviral therapy and increased mortality in the Euro SIDA Cohort: AIDS 2005; 19: 593-601.

Marcellin P, Pequignot F, Delarocque Astagneau E et al., Mortality related to chronic hepatitis B and chronic hepatitis C in France: evidence for the role of HIV co infection and alcohol consumption. J Hepatol 2008: 48: 200-207.

Miailhes P, Traband MA, Pradat P et al., Impact of highly active anti retro viral therapy (HAART) on the natural history of hepatitis B virus (HBV) and HIV co-infection : relationship between prolonged efficacy of HAART and HBV surface and early antigen seroconversion. Clin Infect Dis 2007; 45: 624-632.

Opravil M, Hunziker R, Luthy R et al., Chronic hepatitis B and C in HIV infected patients. Deutsche Med Wockeensch 1998 123: 753-760.

Piroth L, Sene D, Pol S, et al., Epidemiology, diagnosis and treatment of chronic hepatitis B in HIV infected patients (EPIB 2005 STUDY). AIDS 2007: 21: 1323-1331

Puoti M, Torti C, Brunol R Filice G, Carosi G. National history of chronic hepatitis B in co-infected patients. J Hepatol 2006; 44 (suppl): S65-S70.

Puoti M, Bruno R, Sorino V, et al., HIV HCC cooperative Italian–Spanish group Hepatocellular carcinoma in HIV infected patients, Epidemiological features, clinical presentation and outcome AIDS. 2004 Nov 19: 18(17): 2285-93.

Sheng WH, Kao JH, Chen PJ et al., Evolution of hepatitis B serological markers in HIV infected patients receiving highly active anti retro viral therapy. Clin Infect Dis 2007; 45: 1221-1229.

Thio CL, Seaberg EC, Skolasky RL et al., HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multi-Center AIDS Cohort Study (MACS). Lancet 2002; 360: 1921-26

Thio CL, Hepatitis B in the human immunodeficiency virus infected patients: epidemiology, natural history and treatment. Semin Liver Dis. 2003 May; 23(2): 125-36.

Thio CL, Hepatitis B and human immunodeficiency virus. Co-infection. Hepatology 2009; 49/suppl): S138-S145.

UNAIDS. 2008 Report on the global AIDS. Epidemic: HIV and AIDS estimates and data 2001 and 2007. Available at http://data unaids.org/ pub/globalreport/ 2008/jc1510-2008-global-report-pp211-234-en.pdf (accessed 22 october 2008).

UNAIDS 2008, Report on the global AIDS epidemic, UNAIDS, Geneva, Switzerland.

WHO. Hepatitis B. Fact sheet no. 204 Aug 2008. Available at www.who.int/mediacenter/factsheets/fs204/en/ (accassed 22 october 2008)

Weber R, Sabin A, Fris-Moller N et al., Liver related deaths in persons infected with the human immunodeficiency virus: the D: A: D study, Arch Int Med 2006:166: 1632-1641.




DOI: http://dx.doi.org/10.21746/ijbio.2014.06.009

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