PVC workers and their cytogenetic effects

Harikrishnan A., Leena Grace B.*


The industry categories identified vinyl chloride is the chemical used in synthesis for the plastics industry. It is an industrial intermediate chemical that is converted to polyvinyl chloride (PVC) polymer and associated copolymers. It is also used for production of chlorinated solvents, primarily 1, 1, 1-trichloroethane. PVC is used in most industrial sectors and accounts for around one fifth of plastic material usage worldwide. Vinyl chloride liquid is fed to polymerization reactors where it is converted from a monomer to a polymer PVC. The final product of the polymerization process is PVC in either a flake or pellet form. The manufacturing plastics often create large quantities of toxic chemical pollutants such as dioxin, hydrochloric acid, and vinyl chloride.  This poses a severe health risks to humans during the PVC life cycle. These toxins can produce severe illness like cancer, diabetes, neurological damage, reproductive and birth defects. Dioxin is a persistent Organic Pollutant (POP), these are chemical substances that persist in the environment, bio-accumulate through the food chain, and pose a risk of causing adverse effects to human health and the environment. The focal aim of the present study was to identify the genetic effect of PVC workers who were chronically exposed to PVC manufacturing industry in Coimbatore & Tirupur districts. The exposed workers were categorized based on the duration of exposure to PVC chemicals. Moreover, both the exposed subjects and controls were divided according to age wise manner. The groups were divided into four categories namely group. To the best of our knowledge; this is the first kind of study in PVC industry workers in Coimbatore and Tirupur district. The present investigation will definitely gain the consequence of the better resolution to prevent the effects from chemicals entering into the occupationally exposed workers with protection and prevention strategies.


Vinyl chloride; Chromosomes; Genetic effect;l Cell and Environment

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DOI: http://dx.doi.org/10.21746/ijbio.2013.08.0018


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