Oculodermal melanocytosis

Sumana J. Kamath, Dr. Roopashree*, Dr. Vishwaraj


Oculodermal Melanocytosis (ODM) or naevus fuscocoeruleus ophthalmomaxillaris or Nevus of Ota, a melanocytic hyper pigmentation of the globe and periorbital skin, was described in 1939 by Ota and Tanino. Melanocytic hyperpigmentation involving the globe alone is called ocular melanocytosis, and similar hyperpigmentation involvin the skin alone is called dermal melanocytosis. In Caucasians, there is an association between ODM and uveal melanoma. Most cases of the nevus of Ota are unilateral (90%), although pigmentation is present bilaterally in (5%–10%). Ocular abnormalities included pigmentation of the sclera, cornea, retina, and optic disc and cavernous hemangiomas of the optic disc, elevated intraocular pressure, glaucoma, and ocular melanoma. Malignant melanoma of the uveal tract has been reported to occur in patients with ocular or oculodermal melanocytosis. Therefore, all patients with Oculodermal melanocytosis should have periodic ocular examination to allow early detection of glaucoma and uveal melanoma.


Oculodermal melanosis; melanoma; Nevus of Ota

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DOI: http://dx.doi.org/10.21746/ijbio.2013.10.003


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