Antibacterial and antifungal activities of the oxidized product of indole-3- acetic acid by potassium bromate scavenged and unscavenged by mercuric acetate

Deepa D*, Chandramohan G., Chandralekha S., Sumathi P.

Abstract


The oxidation of indole-3-acetic acid by potassium bromate in acetic acid medium was studied.  The oxidation of IAA was done in the presence and absence of the scavenger mercuric acetate. The final product was identified as 3-methylene oxindole by the IR and NMR spectral studies and then examined for biological activity. The antibacterial activity was carried out by agar diffusion method. The antifungal activity of the synthesised product was evaluated by agar diffusion method using potato dextrose agar.

Keywords


Antibacterial activity; Antifungal activity; IAA; Oxidation; Potassium bromate; Scavenger

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DOI: http://dx.doi.org/10.21746/ijbio.2013.02.004

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