In vitro control of selected pathogenic microorganisms by Vernonia adoensis leaves

Ngule Chrispus Mutuku, Anthoney Swamy T.*, Obey Jackie


The main aim of conducting this study was to evaluate antibacterial activity of methanol–water extract of Vernonia adoensis leaves against Salmonella typi, Klebsiella sp, Bacillus cereus, Streptococcus pyogenes, E. coli, Proteus vulgaris and Enterobacter aerogenes. The leaves powders of the plant were extracted with methanol and water in the ratio 9:1. The antibacterial activity of the extract was determined by agar well diffusion method. Vernonia adoensis leaves methanol water extract was found to control the growth of B. cereus, Klebsiella sp., Streptococcus pyogenes  and Escherichia coli at zones of inhibition of 20.17 ± 0.307, 17.33 ± 0.211,11.67 ±  0.494 and  12.17 ±  0.477 respectively. From the study methanol-water extract can be used to control B. creus, Klebsiella sp., Streptococcus pyogenes and Proteus vulgaris. More research needs to be done to identify the specific bioactive compounds.


Vernonia adoensis; Antibacterial activity; Extract; Pathogenic micro-organisms

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