Changes in biochemical parameters of freshwater fish Labeo rohita exposed to lethal and sub-lethal concentrations of indoxacarb

Veeraiah K.*, Srinivasa Rao P., Symyuktha Rani A., Dhilleswarao H.


The Indian major carp Labeo rohita (Hamilton) was exposed to the new generation pesticide Indoxacarb for 24, 48, 72 and 96 h and the acute static LC50 values were determined as 0.0589, 0.05669, 0.05522 and 0.0531 respectively.  These LC50 values indicate that the indoxacarb is highly toxic to fish. The fish were exposed to sub-lethal concentration (1/10th 96 h LC50) for 8 days and the changes in the biochemical constituents of the vital organs viz, Gill, Liver, Brain, Muscle, and Kidney were studied. Significant changes in these organs of fish were observed. The changes were noted as tissue specific and time dependent. Several behavioral changesduring the period of exposure were also observed and noted. The results obtained were discussed at length with the available literature.


Indoxacarb; Labeo rohita; LC50 nucleic acids; and proteins

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