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A case report on Subacute Combined Degeneration of spinal cord in children – A rare neurological manifestation in Vitamin B12 deficiencies

Tiana Mary Alexander, Vineeta Pande, Sharad Agarkhedkar, Dnyaneshwar Upase


Megaloblastic anemia is a common feature between 6 months – 2 years and rarely occurs after 5 years of age, especially in a child consuming non-vegetarian diet. B12 deficiency may occur after 5 years of age because of chronic diarrhea, malabsorption syndrome, or intestinal surgical causes. Pernicious anemia causes B12 deficiency, but nutritional B12 deficiency with subacute combined degeneration causing ataxia is rare.


vitamin B12, degeneration, spinal cord

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Agrawal, Sanwar, and Shweta Nathani. “Neuro-Regression in Vitamin B12 Deficiency.” BMJ Case Reports 2009 (2009): bcr06.2008.0235. PMC. Web. 1 Dec. 2017.

Megaloblastic Anemia in a Child with Central Nervous System Manifestations S.S. Kashyape, P.S. Kashyape and G.M. Kakade Shree Medical Research Center Indian Journal of Pediatrics, Volume 73-January, 2006

Subacute combined degeneration, A description of the case of a strictly vegetarian child Cornejo W, González F, Toro ME, Cabrera D Rev Neurol. 2001 Dec 16-31;33(12):1154-7.



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