Cover Image

Clinical and etiological evaluation of secondary seizures by computed tomography and electroencephalogram

Archana Aher*, Satish Gore

Abstract


This study was conducted to determine the clinical evaluation and various etiological factors of secondary seizures in patients admitted to Government Medical College, Nagpur. We evaluated 58 patients of secondary seizures from Dec 2011 to Oct 2013. Secondary seizures were defined as case of seizure with CT (brain) or MRI (brain) abnormality1. Out of 58 cases 35 were males and 23 were females. Mean age of study subjects was 34.85. The commonest presenting feature was generalized tonic clonic convulsions (42 patients) followed by focal seizures (16 patients).  Todd’s palsy was observed in 4 cases. Aura was present in 24 cases. According to CT brain scan the aetiology was – neurocysticercosis (34.48%), post stroke (27.59%), tuberculoma (24.14%). Space occupying lesions(SOLs) were present in 8 patients, out of whom 4 had brain tumour, 2 patients had brain abscess, 1 had hydatid cyst and 1 had metastasis. Majority of lesions were located in frontal region (58.62%), followed by in parietal region (44.83%), in temporal region (25.86%) and in occipital region (13.79 % patients). In our study neurocysticercosis was found to be the commonest cause of secondary seizures. As in a meta-analysis it was found that cysticidal drugs result in better outcome in patients of neurocysticecosis, we recommend that the patients of secondary seizures should be identified for the aetiology and treated at the earliest2.

Keywords


Secondary seizures; Neurocysticercosis; Computed tomography; Electroencephalogram

Full Text:

PDF

References


Ropper AH, RH Brown. Epilepsy and other seizure disorders. In: Adams and Victor’s principle of neurology, 8th edition. McGraw Hill 2005

Del Brutto OH, KL Roos, CS Coffey, HH Garcia. Meta-analysis: Cysticidal drugs for neurocysticercosis: albendazole and praziquantel. Ann Intern Med 4,145(2005):43-51. Print

Abhirup Biswas, Aradhanab Aparna, Mohanty Satish. Necessity of EEG and CT scan For Accurate Diagnosis of Idiopathic (Partial / Generalized) Seizures in Children. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) 2279-0853, p-ISSN: 2279-0861. 14, 3(Mar. 2015) 05-08. Internet

Gulati PP, SS Kothan, P Wadhwa . Journal of Tropical Medicine and Hygiene :3,131(1991)4.

Kumar N, AS Narayanswamy, VK Gupta, W Singh: EEG and CT scan localization of partial seizures. Neurology India 39(1991) 67-716

Washimkar SN, MP Holay, SM. Fusey Evaluation of focal seizures by computed tomography. JAPI 44(1996)959-60

Ramesh Baheti, BD Gupta, Baheti Rajesh A Study of CT and EEG findings in Patients with Generalised or Partial Seizures in Western Rajasthan. JIACM 4,1(2003) 25-9

Al-Sulamann AA, HM Ismail, Clinical pattern of newly diagnosed seizures in Saudi Arabia: A prospective study of 262 children. Childr. Nerv Sys 15,9 (1998) 968-71.

Doose H, H Lunale, S Waltz, E. Castinglione Severe idiopathic generalised epilepsy of infancy. Neuropediatrics 29,5 (1998): 229-38

Homes S, XS Ni, N Dutt, et al., EEG, CT and neurosonoraphic findings in patients with post-ischaemic seizures. J Neurol Sci 132, 1 (1995) 57-60.

Bogdonoff BM, CR Stafford, L Green, CF Gonzalez. Computerized transaxial tomography in evalution of patients with focal epilepsy. Neurology 25 (1975) 1013-7.

McGohan JP, AB Dubin, RP Hill. The evaluation of seizure disorders by computerised tomography. J. Neurosurg 50(1975) 328-32.

Kramer U, V, Nevo JJ Meyer, et al., Neuroimaging of children with partial seizures. Seizure 7, 2 (1998) 115-8.




DOI: http://dx.doi.org/10.21746/ijbio.2016.10.0013

Refbacks

  • There are currently no refbacks.




Copyright (c) 2016 International Journal of Bioassays

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

International Journal of Bioassays is a member of the Publishers International Linking Association, Inc. (PILA), CROSSREF and CROSSMARK (USA). Digital Object Identifier (DOI) will be assigned to all its published content.