Cover Image

Synthesis and solvatochromic studies of 2- amino-3-phenolazo1-(4-sulfophenyl)-3-methyi-5-pyrozolone and use it for the determination of trace amount of Nickel (II) in blood samples

Amar M. Ali, Hussain. J. Mohammed*

Abstract


A new, simple, sensitive and rapid spectrophotometric method is proposed for the determination of trace amount of Nickel (II). The method is based on the formation of a 1:2 complex with 4-(4-((2-hydroxy-6-nitrophenyl) diazenyl) -3-methyl-5-oxo-2, 5-dihydro-1H-pyrazol-1-yl) benzenesulfonic acid (2-ANASP) as a new reagent is developed. The complex has a maximum absorption at 516 nm and εmax of 1. 84 X 105 L. mol-1. cm-1. A linear correlation (0. 25 – 4. 0μg. ml-1) was found between absorbance at λmax and concentration. The accuracy and reproducibility of the determination method for various known amounts of Nickel (II) were tested. The results obtained are both precise (RSD was 1. 2 %) and accurate (relative error was 0. 787 %). The effect of diverse ions on the determination of Nickel (II) to investigate the selectivity of the method were also studied. The stability constant of the product was 0. 399 X 106 L. mol-1. The proposed method was successfully applied to the analysis of diabetes blood and normal human blood. 

Keywords


Nickel (II) determination; Solvatochromic; 4-(4-((2-hydroxy-6-nitrophenyl) diazenyl)-3-methyl-5-oxo-2; 5-dihydro-1H-pyrazol-1-yl) benzenesulfonic acid

Full Text:

PDF

References


Hussain .M. J. and Aayad. S. A.; Int. J. Chem. Sci.: 13(3), (2015), 1123-1136.

Hussain .M. J. and Aayad .S. A.; Der Pharma Chemica, 7(8), (2015):50-58.

Hussain .M. J., Masar .A. A. and Shaimaa .M. H. Inter. J. of Basic & Appl. Sci IJBAS-IJENS, 15 No:02, (2015), :25-33.

Hussain .M. J. , Azhar. Y. M. and Hayder. A.L.M.; E-Journal of Chemistry, 8(S1), (2011), S425-433.

Masar.A.A and Hussain .M. J. ; Chemical Science Transactions., 3(3), (2014), 1115-1123.

Ikechukwu .E. P. and Peter .A. A. ; Molecules, 20, (2015), 9788-9802.

Perrin .D. D., Agarwal P. R. : "The structures of nickel complexes Biological Systems", Sigel H. C. Ed., vol. 2, (1973), p. 167, Marcel Dekker, New York.

Hughes .N. M.. “Coordination compounds in biology” in Comprehensive Coordination Chemistry, Wilkinson G., Gillard R. D., McCleverty J. A. Eds., vol. 6, (1987), p. 541, Pergamon Press, Oxford.

Andrews .K. R., Blakeley. L. R., Zerner .L. B., R. J. Lancaster, The Bioinorganic Chemistry of Nickel, VCH Publishers New York, U. S. A., (1988), 41-165.

Vereda Alonso .E., Garcia de Torres .A. and Cano Pavon .J. M. ; J. Anal. Atom. Spec, 8, (1993), 843- 846.

Erol .P., Gulsin .A. , Fethiye .G. , Turkan. A. and Musa .M. ; Özcand, Grasas Y Aceites, 59 (3), (2008), 239-244.

kbal Kojuncu .Y´, Jozˇica Majda Bundalevska, U¨ mit Ay, 3 Katarina Cˇ undeva, Trajcˇe Stafilov, and Go¨ksel Akc¸in1 Separation Sci. and Tech. 39, No. 11, (2004), 2751–2765.

Vereda Alonso .E., Cano Pavon .J. M. , Garcia de Torres A. and Siles Cordero.M. T., Analytica &mica Acta, 283, (1993), 224-229.

Ching-Jyi .H. , Jin-Lian .T., Ping-Hua .H. , Shih-Ching L. , Shinine-Ren. L. , Cherng-Chyi T., Talanta 56, (2002), 1109–1115.

Sánchez Rojas .F. , Bosch Ojeda C. and Cano Pavón .M. ; Rese. J. Phar., Bio and Chem. Sci., RJPBCS, 3, (2012), 585,

Taher .M., Mazaheri. L., Ashkenani .H., Mohadesi .A. and Afzali. D. ;Int. J. AOAC, 97(1), , (2014), 225-231.

Vereda Alonso .E., Cano Pavon. J. M., Garcia de Torres A. and Siles Cordero .M. T., Anal Chim. Acta, 283, (1993), 224-229.

. Farghaly .O. A. , Abdel Hameed R. S., Abu-Nawwas .H. , Int. J. Electrochem. Sci., 9, (2014) 3287 – 3318.

Ahmad .S. , Hasan. B., Mohammad .M. ; Cumhuriyet University Faculty of Science Science Journal (CSJ). 36, No: 3, Special Issue (2015).

Alaa .S. and Amirah .S.; J. Saudi. Chem. Soc, 16(4), (2012. )4521-459.

Ravichandran1, D. Benzil1, C. Ramachandraiah1* and K. B. Chandrasekhar, Int. J. Bio, 4. 11, (2015), 4468-4472.

Farukawa .M. and Shibata S, Anal Chim Acta, 140, (1982), 301.

Ooi S., Carter. D., Fernando. Q.; Chem. Commun, 24, (1967), 1301.

Carr .P. W.; Microchem. J, 48, (1993), 4-28.

Johnson .P. B.; Khaledi .G. M. and Dorsey .G. J. ; Anal. Chem. 58, (1986), 2354-2363.

Spange .S.; Keutel .D. and Simon .F.; J. chim, Phys. 89, (1992), 1615-1622.

paley .S. M.; McGzill. A. R.; Moward .C. S. ; Wallace .E. S. ; Harris .M. J. ; Macromole cules, 23, (1990), 4557-4564.

Kamlet .M., Abbound. J., Taft .R. " an examination of linear solvation energy relationship. In progress in physical organic chemistry". Vol. 13, Edited New York (1981), 485-630.

Adel, M. Dusan; Radovan .V. ; Bojan .B. ; Natasa.V; Vesan .V. ; Zeljko .V. andU. Gordana; Chem. Central. J, 6:71, (2012), 2-8.

Hamid .K. and Malihe .E. ; Spectro Chimica. Acta part A, 86, (2012), 39-43.

Anantha lakshmi .P. V. , Jayatyagaraju. V. and Reddy .P. S. , E-Journal of chemistry, 8(1): (2011). 415-420.

El – Enany .N.; Bdel .F. and Rizk .M. Rizk, J. Chin. Chim. Soc., 54, (2007), 941.

Pandey .G. and Narng K. K., Synt. Reas. Inorg. Metrog. Chem., 34, (2004), 291.

Zaki .Z. M., Spectro. Chim. Acta., 56, (2000), 1917.

Boryana .D. , Karima .B. , Elisaventa. I. and Freddy .A. ; Canadian. J. Anal. Sci., 49, No 6, (2004), 346.

Stahr H. M. , "Analytical methods in Toxicology ". 3rd ed. John Wiley and Sons New York (1991), 75.




DOI: http://dx.doi.org/10.21746/ijbio.2016.10.001

Refbacks

  • There are currently no refbacks.




Copyright (c) 2016 International Journal of Bioassays

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

International Journal of Bioassays is a member of the Publishers International Linking Association, Inc. (PILA), CROSSREF and CROSSMARK (USA). Digital Object Identifier (DOI) will be assigned to all its published content.